According to the Kaplan–Meier survival curves, HCC cases with higher HSPA4 expression showed a lower OS (p < 0.001), a poorer disease specific survival (DSS) (p = 0.005), and a progression-free interval (PFI) (p = 0.039) (Fig. 4). The gene discussed is HSPA4; the disease is hepatocellular carcinoma.