ITGAE and neoplasm: Among various subsets of DCs, Batf3-dependent conventional type 1 dendritic cells (cDC1s; migratory CD103+ and lymphoid CD8α+ DCs in mice, and CD141+ DCs in humans) have enhanced abilities to phagocytose dead cells and transport tumor-associated antigens (TAAs) to tumor-draining lymph nodes (TdLN), where they cross-present TAAs to CD8+ T cells16.