MMP11 and gastric cancer: Exosomal miR-27a induces CAFs and promotes tumor cell motility and metastasis by targeting CSRP2.292 Gastric CAFs-derived exosomal miR-139 suppresses gastric cancer metastasis and development by reducing matrix metalloproteinase 11 (MMP11).293 GC cell-derived exosomal miR-130a can be delivered into ECs to induce angiogenesis and tumor growth by regulating c-MYB.294 Studies report that exosomal miRNAs, such as miR-19b-3p, miR-106a-5p, miR-1246, miR-107, miR-196a-1, miR-106a, and miR-155-5p are all upregulated in GC patients.295–300