The diversity of cell populations (i.e. heterogeneity) varied across subtypes, hypodiploid and ERG-deleted tumours were the most heterogeneous (median Simpson index = 0.61 and 0.62; QMann-Whitney = 1.7 × 10−3, 1.13 × 10−3), while hyperdiploid tumours exhibited lower heterogeneity (Simpson index = 0.45; QMann–Whitney = 2.8 × 10−7) (Fig. 7b). This evidence concerns the gene ERG and neoplasm.