Strikingly, we found that miR-934 expression was negatively associated with SHP2 expression in peripheral blood CD8+ T cells (R2 = 0.2330; P = 0.0069; Fig. 5h), indicating that the function of miR-934 in inhibiting tumour progression by acting on SHP2 was reversed by increasing the levels of exosomal circUSP7 in CD8+ T cells. Here, PTPN11 is linked to neoplasm.