Of the 39 PGx drugs, nine drugs (23%) with more than one actionable DGI,including genes coding forCYP2D6, CYP2C19, HLA-A, HLA-B, CYP2C9, CYP4F2or VKORC1 were used by 3.9% of the PGx drug users of the population and9.7% of the PGx drug users of the combined mental disorders casecohorts. This evidence concerns the gene HLA-A and mental disorder.