ACTA1 and Hepatic fibrosis: Furthermore, the changes in morphology, collagen deposition and the protein expression levels of collagen I and α‐SMA caused by sTREM‐1 were little in the Oil‐treated mice, but sTREM‐1 further exacerbated the degree of liver fibrosis in the CCl4‐induced mouse model (Figure 1B‐F).