KCNQ1 and type 2 diabetes mellitus: In the HEXA cohort, light drinkers carrying the ACC haplotype exhibited a higher risk of developing T2DM (odds ratio [OR] 1.530; 95% confidence interval [CI] 1.008–2.323) and the T2DM risk was significantly increased in moderate-to-heavy drinkers carrying ACC haplotype (OR 1.587; 95% CI 1.128–2.234) compared with abstainers not carrying the KCNQ1 ACC haplotype, whereas the T2DM risk was not higher in abstainers carrying the ACC haplotype (OR 1.334; 95% CI 0.888–2.003) compared with non-carriers.