The P-SYK, P-p38, P-JNK, P-PI3K, and P-ERK protein contents in LGBLEL tissues were significantly higher than in CH tissues (P = 0.0169; P = 0.0074; P = 0.0046; P = 0.0157; P = 0.0156, respectively) (Fig. 5B). This evidence concerns the gene MAPK8 and cyclic hematopoiesis.