Since circ_0058106 binds miR-185-3p and regulates miR-185-3p expression, we speculated circ_0058106 may promote HSCC cells tumorigenesis, tumor metastasis and EMT process by regulating Wnt2b/β-catenin/c-Myc pathway via miR-185-3p. The gene discussed is MYC; the disease is neoplasm.