MYC and glioma: Therefore, c-Myc can regulate many biological functions in tumorigenesis, such as cell proliferation, apoptosis, metastasis, EMT process and stemness;[43] c-Myc dysregulation is widespread in different types of human malignancies, including breast cancer [44], glioma [45], liver cancer [46], gastric cancer [47], head and neck cancer [48] and other malignancies, suggesting that c-Myc may be a potential target for cancer treatment.