VEGFA and hepatocellular carcinoma: ELISA also demonstrated that the secretion of VEGF in conditioned medium of HCC cell lines was upregulated by miR-378a-3p mimic and LPS compared with miR-378a-3p mimic alone, while the cells transfected with miR-378a-3p inhibitor and treated with SN50 exhibited lower secretion of VEGF (Fig. S2K).