Moreover, we analyzed the correlation of miR-378a-3p, DNMT1, TRAF1 and VEGFA in TCGA data and found that the expression of miR-378a-3p was significantly inversely correlated with that of DNMT1, TRAF1, and VEGFA in HCC (Fig. S4D-F). This evidence concerns the gene DNMT1 and hepatocellular carcinoma.