Compared to AD group, the content of each pro-inflammation factors (IL-1β, IL-6 and TNF-α) in EA group was significantly lower both in serum and hippocamps (the content of IL-1β and IL-6 in serum and hippocampus, p<0.01; the content of TNF-α in serum, p<0.05; the content of TNF-α in hippocampus, P<0,01). This evidence concerns the gene IL6 and Alzheimer disease.