PARP1 and psoriasis: Our immunohistochemical analysis of psoriasis lesional skin confirmed the drastic induction of NAMPT at protein level and PAR accumulation in the nucleus of epidermal keratinocytes and dermal cells, together with the nuclear translocation of AIFM1, further confirming the relevance of the NAMPT/PARP1/AIFM1 axis in this disease.