In chronic lymphocytic leukemia (CLL) patient samples and cell lines, transcriptomic sequencing revealed that circ-0132266 was involved in tumorigenesis by interacting with miR-337-3p to modulate promyelocytic leukemia protein (PML) expression (108), whereas circ-CBFB contributed to CLL progression by modulating the miR-607/FZD3/Wnt/β-catenin cascade (109). This evidence concerns the gene CBFB and B-cell chronic lymphocytic leukemia.