Moreover, a circRNA microarray was used to compare and analyze expression profiles of three pairs of DLBCL tissues and adjacent tissues and identified circAPC (hsa_circ_0127621), derived from exon 7 to exon 14 of adenomatous polyposis coli (APC) gene, in DLBCL tissues, plasma, and cell lines. The gene discussed is APC; the disease is diffuse large B-cell lymphoma.