Moreover, it is interesting to note that propionylglycine shows a linear correlation with PRKDC, a gene that encodes a protein that acts as a molecular sensor for DNA damage.42 Furthermore, it was previously shown that the PRKDC gene was downregulated in the PBMCs of subjects with type-2 diabetes in comparison with healthy subjects.43 The gene discussed is PRKDC; the disease is type 2 diabetes mellitus.