These genes include glucose transporter (Glut) 1 and Glut3, glycolysis‐related enzymes hexokinase 2 (HK2), glucose‐6‐phosphate isomerase (GPI), phosphofructokinase 1 (PFK1), triosephosphate isomerase 1 (TPI1), enolase 1 (ENO1), pyruvate kinase muscle 2 (PKM2), lactate dehydrogenase A (LDHα), and hypoxia inducible factor 1‐alpha (HIF1α).[28, 32] Surprisingly, we did not observe any significant changes among these enzymes except a minor decrease of PFK1 in both MCF7 and HCT116 tumor cells treated by SCT (Figure S6A, Supporting Information). This evidence concerns the gene PKM and neoplasm.