In a recent study, we found that conditional ablation of murine Wwox in either neural stem cells and progenitors (N‐KO) or neuronal cells (S‐KO mice) resulted in severe epilepsy, ataxia, and premature death at 3–4 weeks, recapitulating the phenotypes observed in the Wwox‐null mice (Repudi et al, 2021). The gene discussed is WWOX; the disease is epilepsy.