The IL-1 family of cytokines has also been implicated in DM and DM-related complications by way of inflammation.265, 266, 267, 268 To better understand the role of IL-1 in the diabetic cornea and corneal wound healing, a recent study utilized a genome-wide cDNA array analysis in normal and DM mouse corneas.268. The gene discussed is IL1B; the disease is diabetes mellitus.