These 19 variants are known eQTLs for seven genes that were also found in the RNA-Seq analysis to be differentially expressed between ALS and control groups (Figures S12 and S13), one of which, integrin subunit alpha V (ITGAV), was identified as dysregulated in each primary assay, WGA, network, and as a fly modifier gene. This evidence concerns the gene ITGAV and amyotrophic lateral sclerosis.