TNF and cancer: The average body mass index was 19.9 kg/m2, and the most frequent comorbidity was diabetes mellitus (14.7%), followed by chronic obstructive pulmonary disease (9.3%), glucocorticoid using (6.7%), malignant tumors (5.8%), transplantation-related immunosuppression (4.25%), chronic renal failure needing dialysis (2.7%), HIV infection (0.1%), illicit drug (0.1%), alcohol using (0.04%), and treatment with TNF-α inhibitors (0.04%).