In the current study, among these type 2 diabetes participants, although none of the urine phthalate metabolites showed a significant association with TPOAb, TgAb, and TPOAb and/or TgAb positivity, different associations between the presence of thyroid antibodies and TSH, FT3, FT4, T4, SPINA-GD, SPINA-GT, TSHI, and TTSI were found. The gene discussed is CD4; the disease is thyroid gland disorder.