DUBR and acute myeloid leukemia: To further reveal that DUBR bind with miR-142-3P in AML, we measured the miR-142-3P in DUBR overexpression KG-1 cells, we found compared with the empty vector group, the miR-142-3P were significantly downregulated by DUBR. Meanwhile, we transfected DUBR siRNA in KG-1 cells, and we found the expression of miR-142-3P could be upregulated by DUBR siRNA (**p < 0.01) (Supplementary Figure S5).