In addition, while the members of the S100A family are broadly engaged in various regulatory processes of inflammatory diseases, such as Kawasaki disease, ischemic heart inflammation, chorioamnionitis, and eye inflammation (Rohde et al., 2014; Tong et al., 2014; Wu et al., 2014; Huang et al., 2018; Golubinskaya et al., 2020), no research has been conducted on the S100A2 gene in ASD immunity so far. Here, S100A1 is linked to eye inflammation.