AHR and chronic rhinosinusitis: Moreover, the AhR is a pivotal effector in many pathological processes (Bock, 2020), such as cancer (Hanieh et al., 2016), intestinal inflammation (Lamas et al., 2016; Metidji et al., 2018), hepatic steatosis (Lee et al., 2010), chronic rhinosinusitis (Liu et al., 2018), and atopic dermatitis (van den Bogaard et al., 2013; Peppers et al., 2019).