In this study, we found that the genotype distribution of PNPLA3 rs738409, TM6SF2 rs58542926, LPIN1 rs13412852, KLF6 rs3750861, SOD2 rs4880, and ZNF624 rs12603226 SNPs was not different in the diabetic vs. non-diabetic population, whereas their distribution was different between the patients with NAFLD and the patients without NAFLD irrespective of presence of diabetes. The gene discussed is LPIN1; the disease is metabolic dysfunction-associated steatotic liver disease.