Particularly, both the patients with diabetes and non-diabetic ones had a higher frequency of PNPLA3 rs738409G allele in NAFLD group (GG genotype prevalence was 11% in the NAFLD patients vs. 4% in control group and GC genotype prevalence was 45% in NAFLD group vs. 40% in the individuals without liver steatosis). Here, PNPLA3 is linked to metabolic dysfunction-associated steatotic liver disease.