Accordingly, an advanced new model was generated: logit (MCI) = −9.87434 + 0.03576 × age + 0.58996 × (ApoE ε4 = 1) + 1.83487 × rGSK-3β(Total/S9) + 0.53539 × olfactory score + 1.01532 × Aβ1-42/Aβ1-40, which could be used to precisely discriminate MCI from T2DM patients. Here, APOE is linked to type 2 diabetes mellitus.