EIF5A and pancreatic ductal adenocarcinoma: With respect to the other genes, EIF5A, a eukaryotic translation initiation factor, enhances the expression of a series of proliferation-associated proteins essential for cancer cells and is upregulated in several cancers, including pancreatic ductal adenocarcinoma, glioblastoma, leukemia, liver, colon, lung, cervical, and ovarian cancer (Mathews and Hershey, 2015; Strnadel et al., 2017).