TP53 and lung adenocarcinoma: In fact, lung adenocarcinoma can be classified by genetic mutations in TP53 (46%), KRAS (32%), EGFR (27%), and KEAP1 (23%), among others (14, 49, 50) and SCC may have mutations in TP53 (90%), KEAP1 (31%), and PTEN (15%) and others (Table 1) (50–52).