SLC1A5 and non-small cell lung carcinoma: Studies in NSCLC using the glutamine analogue L-γ-Glutamyl-p-nitroanilide (GPNA) revealed that glutamine is transported through SLC1A5 and that this transporter is required for proliferation in glutamine-dependent cell lines (A549, HCC15, and H520), which was confirmed using siRNA against SLC1A5 (Table 2 and Figure 3) (133).