The results showed that oeAR (over-expressing AR) could decrease HCC Hep3B cells’ invasion and migration capacities (Figures 1A–C), and shAR (knocking down AR) led to the increase of the invasion and migration capacities of HCC PLC/PRF/5 cells (Figures 1D–F), which was also consistent with our previous data (16, 17). This evidence concerns the gene AR and hepatocellular carcinoma.