Then, the RNA expression of genes from the EGFR signaling axis (KRAS, NRAS, BRAF, EGFR, and MET), a tumor stem cell marker (PROM1), EGFR-resistance genes (TRAP1, AXL, PRSS1, and EPHA2) and EGFR-sensitive genes (ERBB3, ERBB2, EREG, AREG, NT5E, and PTEN, summarized in Table 1) were mapped across the pseudotime trajectory (Figure 1B). Here, EGFR is linked to neoplasm.