<h4>Purpose</h4>To compare the diagnostic performance of <sup>68</sup>Ga-PSMA-11 PET/CT and mpMRI for pelvic lymph node staging prior to radical prostatectomy in prostate cancer (PCa) patients based on per patient data.<h4>Methods</h4>PubMed and Embase databases were searched until October 2020 for eligible studies evaluating head-to-head comparison of <sup>68</sup>Ga-PSMA-PET/CT and mpMRI for the detection of pelvic lymph node metastases (PLNMs) using pelvic lymph node dissection (PLND) as gold standard. The gene discussed is FOLH1; the disease is metastatic malignant neoplasm in the lymph nodes.