Right supraclavicular lymph node biopsy was performed, and pathological examination allowed diagnosis of lung adenocarcinoma T2N3M1a (Figure 2A), and immunohistochemistry (IHC) revealed the tumor to be NapsinA+, TTF-1+, CK7+, CD10−, and vimentin+. The gene discussed is KRT7; the disease is lung adenocarcinoma.