found that splicing factor SRSF10 can bind to Alu elements on both sides of the circ-ATXN1 pre-mRNA (74), thus promoting the generation of circ-ATXN1 and promoting the proliferation, migration and tube-forming capacity of GECs (glioma-exposed endothelial cells, GECs) via circ-ATXN1/miR-526b-3p/MMP2/VEGFA pathway. The gene discussed is VEGFA; the disease is central nervous system cancer.