CASC2 and neoplasm: The lncRNAs including PCAT-1, DANCR, SNHG5, GEHT1, ANRIL and so on were identified as oncogenes to promote the gastric cancer cell progression and chemoresistance (20–24); on the other hand, the lncRNAs such as CASC2 and CRAL have been found to act as a tumor-suppressor to attenuate gastric cancer progression (25).