EZH2 and glioblastoma: Chen et al. specified that the GBM-linked lncRNA NEAT1 was an oncogenic factor that was modulated via the EGFR pathway and triggered tumorigenesis by acting as a scaffold as well as recruiting the chromosome modification enzyme EZH2 to knock down target-specific genes like AXIN2, ICAT, and GSK3B which facilitated β-catenin nuclear transport (Figure 2) [104].