LRRK2 and Alzheimer disease: Several genes are implicated in AD (CACNA1C, CALM1, CALM2, CALM3, IDE), circadian entrainment (CACNA1C, CALM1, CALM2, CALM3), and dopamine signaling (CACNA1C, CALM1, CALM2, CALM3, LRRK2).LRRK2 is the only gene in the network linked to PD.