ForHLA-DQB1, 1.2% of the correlates are common in all brain regions; relevant associated themes include PD and dopamine (SLC18A1) insulin (HLA-DRB5, HLA-DOA, HLA-DQA1, HLA-DQB1) and transcription factors (FOXE3, HMGB1, LGALS9, PYCARD, SOX8, ZNF446). This evidence concerns the gene HMGB1 and Parkinson disease.