In medical imaging research, Koshima et al. used chemical methods such as endothelial specific gene overexpression and fluorescent immunohistochemistry to study the role of cerebrovascular protein in the formation of atherosclerosis in adult patients and showed that cerebrovascular protein aggravated the damage of atherosclerotic endothelial cells by activating nitrosative stress and NLRP3 inflammatory bodies [2]. The gene discussed is NLRP3; the disease is atherosclerosis.