Recent studies also identified some key ferroptosis-related gene signature, such as glutathione peroxidase 4 (GPX4), solute carrier family 7 member 11 (SLC7A11), nuclear respiratory factor 2 (NRF2), and cysteine dioxygenase type 1 (CDO1), which are closely related to cancer progression and patients' prognosis [13–16]. Here, GPX4 is linked to cancer.