The increase of ROS/RNS resulting from the combination of different configurations of gas plasma with FAK antibody conjugated-AuNPs, silica, silver, iron oxide, cerium oxide, titanium oxide, iron-doped titanium oxide NPs, and Anti-EGFR-AuNPs leads to a significant increase of early apoptosis and secondary necrosis, reduction in G2/M levels, increase in the sub-G1 fraction, FAS externalization, caspase-8 activation, increase of selective cancer cell death, inhibition the viability of cancer cells, and reduction of growth pattern [163–167]. Here, CASP8 is linked to cancer.