However, FHL1 expression is increased in idiopathic pulmonary arterial hypertension patients, in patients with LV hypertrophy and hypertrophic cardiomyopathy (Hwang et al. 1989; Lim et al. 2001), as well as in mice with agonist, pressure or volume-overload cardiac hypertrophy (Chu et al. 2000b; Gaussin et al. 2003; Hutchinson et al. 2015). The gene discussed is FHL1; the disease is hypertrophic cardiomyopathy.