CARM1 and cancer: Different human cancer cases with altered CARM1 showed the poorer prognosis in progression-free survival (P = 0.013), but not overall survival (P = 0.311), disease-free (P = 0.103), and disease-specific (P = 0.0626) relative to cases without CARM1 variations (Figure 4(e), Supplementary Figure S2).