When tumors and their matched adjacent tissues were involved in the TCGA database, the expression of CARM1 was elevated in BRCA, bladder urothelial carcinoma (BLCA), COAD, CHOL, HNSC, ESCA, lung adenocarcinoma (LUAD), LIHC, STAD, and LUSC, while its decreased expression was also observed in KIRC and kidney chromophobe (KICH) via the TIMER database (Supplementary Figures S1a and S1b). This evidence concerns the gene CARM1 and lung adenocarcinoma.