TG and hypophosphatasia: The obvious difference in thyroid hormone levels between the two analyzers, both of which adopted ALP for signal enhancement and identical antibody sets, prompted us to measure FT3 and FT4 levels in these three HPP patients undergoing asfotase alfa treatment with other analyzers utilizing different measuring systems, including AccuraSeed, ARCHITECT i2000SR, and Cobas8000 e801 (Table 1).