CREM and neoplasm: In the sarcoma assay, EWSR1 was the most commonly rearranged gene in our case series, with 3′ partners including FLI1, ERG, WT1, CREB1, ATF, PBX3, CREB3L1, TFCP, NR4A3, NFATC2, POU5F1, DDIT3, CREM, PATZ1, and COLCA2 in a wide variety of tumor types.