In the sarcoma assay, EWSR1 was the most commonly rearranged gene in our case series, with 3′ partners including FLI1, ERG, WT1, CREB1, ATF, PBX3, CREB3L1, TFCP, NR4A3, NFATC2, POU5F1, DDIT3, CREM, PATZ1, and COLCA2 in a wide variety of tumor types. This evidence concerns the gene POU5F1 and neoplasm.