We further introduced several published transcriptomic-based predictors as previous study (Lee et al., 2021), including the proliferation index (Whitfield et al., 2006), interferon-γ (IFNγ) signature score (Ayers et al., 2017) as well as cytolytic activity score (Rooney et al., 2015), and performed a multivariate Cox regression analysis with age, tumor stage, and our classifier (Supplementary Figure S2). This evidence concerns the gene IFNG and neoplasm.