PPARA and amebiasis: The results showed that the pretreatment group had significant higher pathway associated with cytochrome P450 while lower meiosis-yeast, alpha-linolenic acid metabolism, hematopoietic cell lineage, citrate cycle (TCA cycle), PPAR signaling pathway, adipocytokine signaling pathway, peroxisome, and amoebiasis than the post-treatment group (p<0.05) (Figure 4A).