IFIH1 and retinitis pigmentosa 1: Indeed, although some studies report a much higher frequency of RP-ILD in Japanese anti-MDA5 JDM patients associated with a poor prognosis, a recent multicenter study reported only 19% of RP-ILD in a cohort of 31 anti-MDA5 Abs positive patients, with a lower rate of relapse than other MSA positive patients (63, 67, 68).