Furthermore, gene co-expression analyses, conducted to explore the relationship between FUCA2 expression and immune-related genes in pan-cancer, revealed that FUCA2 expression was positively correlated with most MHC genes (Figure 8A), immunosuppressive genes (Figure 8B), chemokines (Figure 8C), and chemokine receptors (Figure 8D) across most tumor types (Supplementary Table 1). The gene discussed is HLA-C; the disease is cancer.