Given our current finding and the high frequency of deletions and mutations of TRAF3 detected in human NHL and MM (13, 14), we searched the Cancer Genome Atlas (TCGA) (73) and the Catalog of Somatic Mutations in Cancer (COSMIC) (74) databases for the potential presence of genetic alterations of MFF and DNM1L in human B cell malignancies. Here, TRAF3 is linked to cancer.