Based on the next-generation sequencing of EVs obtained from endometriosis patient plasma–derived extracellular vesicles compared with healthy control extracellular vesicles, studies have documented that differential expression of miR-16 and -30d regulating the angiogenic function by targeting the VEGF and MYPT1/cJUN/VEGFA pathway, respectively. This evidence concerns the gene VEGFA and endometriosis.