PRL and neoplasm: Considering the increased levels of PRL in the serum of patients with EC, compared to the serum PRL levels of patients with other types of neoplasms, PRL has been proposed as a strong, sensitive (98.3%) and specific (98.0%) biomarker for the early detection of EC (100), and its combination with other biomarkers could improve the sensitivity and specificity of the EC diagnosis (2, 4, 6, 100–102).